Table 3. Risk of CRC associated with the nine common European haplogroups.
Frequency (%)
|
Adjusted resultsa
|
Unadjusted results
|
||||
---|---|---|---|---|---|---|
Haplogroup | Case | Control | P-value | OR (95% CI) | P-value | OR (95% CI) |
H | 1258 (44.1) | 1261 (44.7) | 0.59 | 0.99 (0.94–1.04) | 0.65 | 0.99 (0.94–1.04) |
I | 98 (3.4) | 88 (3.1) | 0.57 | 1.04 (0.90–1.21) | 0.50 | 1.05 (0.91–1.22) |
J | 300 (10.5) | 263 (9.3) | 0.12 | 1.07 (0.98–1.17) | 0.13 | 1.07 (0.98–1.17) |
K | 184 (6.4) | 213 (7.5) | 0.10 | 0.92 (0.83–1.02) | 0.10 | 0.92 (0.83–1.02) |
T | 303 (10.6) | 306 (10.8) | 0.91 | 1.00 (0.91–1.08) | 0.78 | 0.99 (0.91–1.07) |
U | 452 (15.8) | 430 (15.2) | 0.47 | 1.03 (0.96–1.10) | 0.53 | 1.02 (0.95–1.10) |
V | 104 (3.6) | 108 (3.8) | 0.64 | 0.97 (0.84–1.11) | 0.72 | 0.97 (0.85–1.12) |
W | 67 (2.3) | 76 (2.7) | 0.33 | 0.92 (0.78–1.09) | 0.41 | 0.93 (0.79–1.10) |
X | 42 (1.5) | 31 (1.1) | 0.21 | 1.16 (0.92–1.47) | 0.21 | 1.16 (0.92–1.46) |
Undefined | 46 (1.6) | 46 (1.6) | 1.00 | 1.00 (0.81–1.23) | 0.96 | 0.99 (0.81–1.22) |
CI=confidence interval; OR=odds ratio.
Adjusted for age and gender.