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. 2008 Nov 18;99(12):2020–2028. doi: 10.1038/sj.bjc.6604783

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Copyright © 2008 Cancer Research UK

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Immunohistochemical staining of phosphorylated extracellular-regulated kinase (p-ERK1/2). (A) Intense immunoreactivity is present in both the nucleus and the cytoplasm in this ovarian carcinoma. (B) A case with negative staining of phosphorylated ERK1/2 (p-ERK1/2).