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. Author manuscript; available in PMC: 2009 Feb 15.
Published in final edited form as: J Infect Dis. 2008 Feb 15;197(4):519–526. doi: 10.1086/526787

Table 4.

Adjusted differences in malaria-related clinical outcomes for Kenyan children with and those without high levels of IgG antibodies to circumsporozoite protein (CSP), liver-stage antigen type 1 (LSA-1), and thrombospondin-related adhesive protein (TRAP).

Risk of clinical malaria
Cumulative incidence of malaria (multiple episodes)
Change in Hb level, g/dL
Antigens HR (95% CI) Pa IRR (95% CI) Pb Mean difference (95% CI) Pc
CSP, LSA-1, TRAP 0.29 (0.10–0.81) .02 0.29 (0.11–0.74) .009 +1.00 (+0.25 to +1.75) .009

CSP, LSA-1 0.43 (0.21–0.88) .02 0.58 (0.31–1.08) .09 +1.07 (+0.45 to +1.68) .001

NOTE. All values are adjusted for age, bed net use, and parasitemia at the time of enrollment. CI, confidence interval; HR, hazard ratio; IRR, incidence rate ratio.

a

By Cox regression analysis.

b

By negative binomial regression analysis.

c

By multiple linear regression analysis.