Figure 4.

Diagram showing the primary circuits and neurotransmitters implicated in reinstatement by drugs, cues and stressors. VTA, ventral tegmental area, cell body regions of mesocorticolimbic DA pathway; NAc, nucleus accumbens; mPFC, medial prefrontal cortex; VP/SNr, ventral pallidum/substantia nigra reticulata; PPT/LDT, peduncular pontine and laterodorsal tegmental nuclei; BLA, basolateral amygdala; HIPP, hippocampus; CeA, central nucleus of the amygdala; BNST, bed nucleus of the stria terminalis; LTN, lateral tegmental nuclei; NA, noradrenaline. Dark grey, dopamine; black, glutamate; light grey, CRF; black dots, noradrenaline.