Figure 6.

TEM images of the MCF-7 cells, (a) before and 5 hours post treatment with (b) ODNs–membranes complexes. Multiple electron-dense inclusion bodies (ODN–cubic membrane complexes) are frequently observed within the cytoplasm and some targeted the nucleus (N) of the treated MCF-7 cells (b) while there are no such inclusion bodies observed in MCF-7 cells before ODN treatment (a). At higher magnification, membrane association was frequently observed between electron-dense inclusion bodies and nuclear membranes (c). Data are from a representative experiment performed at least three to five other times with similar findings.