Figure 2.

Concentration dependent augmentation of fibroblast-mediated collagen gel contraction. Increasing numbers of platelets were mixed together with fibroblasts in a three-dimensional collagen gel. After gelation, the gels were released and the area of the floating gels was measured after 48 hours of culture. Vertical axis: gel area expressed as percentage of original gel size. Horizontal axis: number of platelets added to gels. Data shown as mean of triplicate ± SEM. P < 0.001: 0 (HFL1) vs. 10⁷ at all data points.