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Fibroblast-mediated collagen gel contraction is dependent of cell concentration. Increasing number of fibroblasts (HFL1) were added to three-dimensional collagen gels. After gelation, the gels were released and the area of the floating gels was measured after 48 h of culture. Vertical axis: gel area expressed as percentage of original gel size. Horizontal axis: number of fibroblasts added to gels. Data shown as mean of gel triplicate and ± SEM.
