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Release of PDGF-AB and TGF-β1 in co-culture. Fibroblasts (HFL1) or fibroblasts together with platelets (Plt), fixed platelets (fix Plt) or platelet lysate (Lys) were cast into collagen gels. After two days of culture, the media surrounding the gels were collected and analysed for a) PDGF-AB and b) TGF-β1 (ELISA). Vertical axis: total concentration of PDGF-AB respectively TGF-β1 (pg/mL). Data shown as mean of duplicates ± SD. *** P < 0.001.
