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Histomorphologies of cartilage- and bone-like regions. (a,b) Representative histological sections are shown for tissue constructs cultured individually for the first three weeks in OSM or CHM, and (c–h,k–p) for the cartilage-like (CLT) and bone-like (BLT) regions of composites cultured for an additional three weeks in chondrogenic, osteogenic or control medium. Stains: (a–h) von Kossa and (i–p) collagen type I immunostain (scale bars, 100 μm).
