Table 2.
Treatment strata | Coefficient *(standard error) | R2* | P-value |
---|---|---|---|
OHA dose(s) unchanged | −0.2 (0.01) | 0.08 | 0.04 |
OHA dose(s) increased | −0.09 (0.02) | 0.02 | 0.63 |
New OHA added | −0.4 (0.03) | 0.05 | 0.21 |
OHA dose(s) increased and new OHA added | −0.9 (0.03) | 0.04 | 0.002 |
Insulin added | −0.5 (0.01) | 0.03 | <0.001 |
All subjects | −0.06 (0.01) | 0.04 | 0.38 |
*Coefficients represent change in A1c for every ten glucose test strips used each week. Coefficients and R2 were derived for each outcome stratum using separate multivariate linear regression models adjusting for initial doses of glyburide and metformin and the number of oral hypoglycemic agents at entry
Abbreviations: OHA = oral hypoglycemic agent