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. Author manuscript; available in PMC: 2009 Oct 20.
Published in final edited form as: J Biomech. 2008 Sep 20;41(14):2964–2971. doi: 10.1016/j.jbiomech.2008.07.033

Figure 1. Mechanical responses of a tissue construct and its constituents to a rapid stretch.

Figure 1

(a) Characteristic rapid rise, rapid shedding (~2 sec), rapid (RAR: ~50 sec) active recovery, plateau, and gradual (GAR: ~1000 sec) active recovery of tissue tension in a preconditioned tissue construct. (b) The extracellular matrix (ECM) contribution to overall tissue construct response, estimated by removing cells through treatment with Triton 100-X. The ECM response was entirely passive. (c) The cellular response, estimated by subtracting Figure 1b from Figure 1a.