Table 1.

Model accuracy on evaluation dataset (30% independent data) using AUC. (Standard deviations (±) indicate the variability of model accuracy through 100 iterations. AUC values for models calibrated in Europe (EU), North America (NA) and both (EU+NA) are indicated for each modelling technique. The differences in model accuracy between ranges within and between models were tested with a paired Wilcoxon signed-rank test (n.s., not significant; ^*0.05<p<1×10⁻⁵; ^**p<1×10⁻⁵).)

	calibration in EU			↔	calibration in EU+NA			↔	calibration in NA
	NA	↔	EU		EU	↔	NA		NA	↔	EU
GLM	0.77±0.07	**	0.87±0.03	n.s.	0.86±0.03	**	0.96±0.01	n.s.	0.96±0.01	**	0.73±0.04
GAM	0.89±0.05	*	0.88±0.03	n.s.	0.87±0.03	**	0.96±0.01	n.s.	0.96±0.01	**	0.70±0.04
GBM	0.85±0.02	**	0.89±0.03	n.s.	0.88±0.03	**	0.96±0.01	n.s.	0.97±0.01	**	0.76±0.04
RF	0.84±0.03	**	0.90±0.02	n.s.	0.90±0.03	**	0.97±0.01	n.s.	0.98±0.01	**	0.76±0.03