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. 2007 Sep 6;363(1492):761–776. doi: 10.1098/rstb.2007.2182

Table 1.

Comparison of aspects related to the development and application of chemical and biological control. (Updated to 2004; adapted from van Lenteren (1997a,b).)

chemical control biological control
number of ‘ingredients’ tested >3.5 million 3000
success ratio 1 : 200 000 1 : 20
developmental costs 180 million US$ 2 million US$
developmental time 10 years 10 years
benefit per unit of money invested 2.5–5 30
risk of resistance large nil/small
specificity low high
harmful side effects many nil/few