Table 1.

G-proteins implicated in Wnt and Frizzled signalling. (PCP, planar cell polarity; PDE, cGMP-specific phosphodiesterase; PKC, protein kinase C; PLC, phospholipase Cβ; AC, adenylate cyclase; PKA, protein kinase A; CamKII, calcium–calmodulin-dependent kinase II.)

G-protein subunit	downstream mediators	references
αo	β-catenin	Katanaev et al. (2005)
	β-catenin	Liu et al. (2001)
	β-catenin	Liu et al. (2005)
	PCP signalling	Katanaev et al. (2005)
	PDE	Ma & Wang (2006)
	PKC	Liu et al. (1999a)
	differentiation assay	Liu et al. (1999b)
αt2	PDE	Ma & Wang (2006)
	PDE	Ahumada et al. (2002)
	differentiation assay	Liu et al. (1999b)
αq	β-catenin	Liu et al. (2001)
	β-catenin	Liu et al. (2005)
	PLC/PKCδ	Tu et al. (2007)
	PKC	Liu et al. (2001)
α11	PLC/PKCδ	Tu et al. (2007)
αs	AC/PKA	Chen et al. (2005)
αi	AC/PKA	Park et al. (2006)
βγ	PLC/PKC/cdc42	Penzo-Mendèz et al. (2003)
	PLC	Slusarski et al. (1997a)
	PLC/CamKII	Kuhl et al. (2000)
	PLC/PKC	Sheldahl et al. (1999)
	differentiation assay	Liu et al. (1999b)