Figure 2.

Migration of cranial and trunk NC. Different factors that control the migration in the cranial and trunk NC are shown. Arrows represents streams of migrating NC. Cranial NC: migration in the head is controlled by Eph/ephrins and semaphorins/neuropilins. The expression of the different factors is shown in the rhombomeres (rb) and in the NC and mesoderm (nc&m). Trunk NC: migration in the trunk: I, ventromedial migration controlled by Slit/Robo; II, dorsolateral migration controlled by Eph/ephrins; III, ventromedial migration controlled by semaphorins/neuropilins. In addition, the anterior–posterior (A–P) patterning of NC migration is controlled by Eph/ephrins and semaphorins/neuropilins. See text for details.