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Monotherapy Results of a Recent Meta-Analysis
| Monotherapy Treatment | Malformations | |
|---|---|---|
| Number of Fetuses | Percent (95% Confidence Interval) | |
| None (women without epilepsy) | 108,084 | 3.27 (1.37–5.17) |
| Carbamazepine | 4,411 | 4.62 (3.48–5.76) |
| Lamotrigine | 1,337 | 2.91 (2.00–3.82) |
| Phenobarbital | 945 | 4.91 (3.22–6.59) |
| Phenytoin | 1,198 | 7.36 (3.60–11.11) |
| Valproate | 2,097 | 10.73 (8.16–13.29) |
| Reference: Meador et al. (18) | ||
