Figure 1.

Interactions between PP and SC inputs in the CA1 region. A, The diagram depicts the slice preparation used for these studies. The SC pathway was activated in the apical dendritic region by separate stimulating electrodes (S-Stim) placed on either side of recording electrodes in the CA1 region. The PP (P-Stim) was activated by a stimulating electrode placed near the EC where the PP enters the hippocampus. B, The panel depicts interactions between PP and SC inputs to CA1 using a paired-pulse protocol and a 20 ms interpulse interval. Traces show examples of raw data, whereas the graph shows the time course of change in EPSPs recorded in stratum radiatum after conditioning stimulation of the PP (black squares) or SC (white circles). Calibration: 1 mV, 5 ms. Error bars indicate SEM.