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. Author manuscript; available in PMC: 2009 Oct 1.
Published in final edited form as: J Immunol. 2008 Oct 1;181(7):5089–5097. doi: 10.4049/jimmunol.181.7.5089

FIGURE 1.

FIGURE 1

IFNγ inhibits LPS- and PMA-induced MMP expression in primary monocytes. A-C, Primary human monocytes were stimulated with 100 ng/ml of LPS with or without IFNγ pre-treatment (100 U/ml, added 3 hr before LPS) for 3 hr (A and C), or 12 hr (B). D, PMA (100 ng/ml) stimulation of primary monocytes in the absence or presence of IFNγ pre-treatment. mRNA levels were analyzed using real time PCR and normalized relative to β-Actin; results are expressed as mean ± SD of triplicate determinants. Results are shown as expression in stimulated monocytes relative to expression in unstimulated cells (control), which was set at 1.