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. Author manuscript; available in PMC: 2009 Oct 1.
Published in final edited form as: J Immunol. 2008 Oct 1;181(7):5089–5097. doi: 10.4049/jimmunol.181.7.5089

FIGURE 3.

FIGURE 3

IFNγ inhibition of LPS-induced MMP expression is dependent on STAT1. THP-1 cells transduced with control DSRed2-shRNA- or STAT1-shRNA-encoding lentiviral particles were stimulated with 100 ng/ml of LPS (3 hr) with or without IFNγ pre-treatment (100 U/ml, added 3 hr before LPS) and mRNA levels were measured using real time PCR and normalized relative to β-Actin. Results are expressed as mean ± SD of triplicate determinants. Results are shown as expression in stimulated monocytes relative to expression in unstimulated cells (ctrl), which was set at 1.