Table 2. Candidate gene studies for age-related macular degeneration.
|
Chromosome |
Gene |
| 1 |
ABCA4, HEMICENTIN (Fibulin 6) |
| 3 |
CX3CR1 |
| 6 |
HLA genes, VEGF, ELOVL4, SOD2 |
| 7 |
PON1 |
| 9 |
VLDLR, TLR4 |
| 12 |
LRP6 |
| 14 |
Fibulin 5 |
| 17 |
ACE |
| 19 |
APOE |
| 20 | CST3, MMP9 |
Genes with at least one positive result to date. For a comprehensive review of these genes including references, see Haddad et al. [17].