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. 2008 Jun 16;69(2):520–533. doi: 10.1111/j.1365-2958.2008.06305.x

Fig. 4.

Fig. 4

Effect of pyrimidines on growth. Cells were grown in HMI9 medium supplemented with varying amounts of pyrimidines for 72 h and cell density was determined using Alamar Blue as described in Experimental procedures.

A. WT plus thymidine, open circles; SKO plus thymidine, closed circles.

B. DKO plus thymidine, closed squares; DKO plus thymine, open squares (a complete lack of growth stimulation was also observed with uracil or uridine). The dashed line is the best fit for growth stimulation and the dotted line is the best fit for growth inhibition.