TABLE 1. Physiological Variables in Outcome Experiment.
Values are mean (SD). All variables were similar between groups.
| Saline (N=17) |
BDNF (N=15) |
|
|---|---|---|
| Baseline | ||
| Weight (g) | 320 (20) | 317 (24) |
| Anesthesia Duration (min) | 44 (6) | 38 (14) |
| Heart Rate (beats / min) | 334 (40) | 341 (20) |
| Mean Blood Pressure (mmHg) | 107 (8) | 112 (8) |
| PH | 7.44 (0.03) | 7.44 (0.02) |
| PCO2 (torr) | 45 (3) | 45 (3) |
| PO2 (torr) | 152 (38) | 167 (36) |
| Glucose (mg/dl) | 137 (26) | 126 (18) |
| CPR Duration (s) | 49 (7) | 56 (15) |
| 10 minutes after cardiac arrest | ||
| Heart Rate (beats / min) | 444 (33) | 438 (26) |
| Mean Blood Pressure (mmHg) | 164 (23) | 170 (18) |
| PH | 7.34 (0.05) | 7.34 (0.05) |
| PCO2 (torr) | 41 (5) | 41 (5) |
| PO2 (torr) | 261 (33) | 275 (66) |
| Glucose (mg/dl) | 141 (54) | 142 (52) |
| Lactate (mEq/l) | 4.1 (1.3) | 4.3 (0.7) |
| 30 minutes after cardiac arrest | ||
| Heart Rate (beats / min) | 437 (43) | 432 (32) |
| Mean Blood Pressure (mmHg) | 88 (27) | 95 (19) |
| PH | 7.43 (0.04) | 7.41 (0.04) |
| PCO2 (torr) | 42 (5) | 45 (5) |
| PO2 (torr) | 374 (39) | 387 (45) |
| Glucose (mg/dl) | 96 (19) | 93 (13) |
| Lactate (mEq/l) | 1.3 (0.6) | 1.7 (1.1) |
| 60 minutes after cardiac arrest | ||
| Heart Rate (beats / min) | 355 (30) | 351 (50) |
| Mean Blood Pressure (mmHg) | 81 (28) | 89 (25) |
| PH | 7.42 (0.05) | 7.40 (0.05) |
| PCO2 (torr) | 44 (7) | 47 (6) |
| PO2 (torr) | 411 (24) | 442 (43) |
| Glucose (mg/dl) | 96 (17) | 107 (9) |
| Lactate (mEq/l) | 0.8 (0.3) | 0.9 (0.4) |