Table 2.
Outcome Measures at Baseline of ADAPT Subjects Utilized for Biomarker Studies, by Intervention Arm
| Diet+Exercise N=46 |
Diet N=48 |
Exercise N=46 |
Control N=53 |
P-Value | |
|---|---|---|---|---|---|
| Mean (SE) | Mean (SE) | Mean (SE) | Mean (SE) | ||
| KL score | 2.52 (0.14) | 2.54 (0.11) | 2.50 (0.13) | 2.51 (0.13) | .99 |
| WOMAC Function | 23.38 (1.76) | 17.76 (1.74) | 25.33 (1.74) | 22.42 (1.67) | .02 |
| WOMAC Pain | 6.33 (0.53) | 5.11 (0.53) | 7.39 (0.53) | 6.42 (0.51) | .03 |
| WOMAC Stiffness | 3.53 (0.22) | 2.78 (0.22) | 3.87 (0.22) | 3.36 (0.21) | .01 |
| Distance walked (ft) | 1472 (46.9) | 1392 (38.7) | 1535 (48.9) | 1485 (44.6) | .17 |
| Stair climb time (s) | 9.14 (0.64) | 9.12 (0.84) | 9.90 (1.55) | 9.85 (0.82) | .91 |
| JSW_LA (mm) | 4.89 (0.20) | 4.70 (0.17) | 4.63 (0.22) | 4.72 (0.18) | .81 |
| JSW_MED (mm) | 3.34 0.24) | 3.17 (0.21) | 3.47 (0.22) | 3.23 (0.24) | .80 |
KL= Kellgren-Lawrence; WOMAC = Western Ontario and McMaster Universities Osteoarthritis Index; ft = feet; s= seconds; JSW = joint space width; LA= lateral; MED=medial; mm=millimeters