Table 5.

Association between baseline biomarker levels and outcome measures, adjusting for age, gender, BMI (except for weight), baseline value, group and visit.

Outcomes	HA	AgKS	COMP	TGF-β1
WEIGHT	−.003 (.023) .90	.02 (.01) .01	.12 (.16) .46	.02 (.08) .78
WOMC function	−.0004 (.001) .77	−.001 (.0004) .16	−.01 (.01) .24	.0005 (.005) .92
WOMC pain	−.001 (.001) .38	−.003 (.001) .50	−.01 (.01) .49	−.003 (.005) .46
WOMC stiffness	.00002 (.002) .99	−.001 (.001) .03	−.01 (.01) .22	−.004 (.01) .45
Distance walked	.58 (.63) .36	.13 (.20) .53	−6.5 (4.24) .13	−.71 (2.00) .72
Stair climb time	−.01 (.01) .19	.01 (.004) .08	−.08 (.08) .30	−.03 (.04) .49
JSW lateral	−.001 (.002) .67	.0002 (.001) .74	.02 (.01) .17	−.01 (.01) .52
JSW medial	−.004 (.002) .10	.001 (.001) .46	.01 (.01) .55	.01 (.01) .26
K-L score	.001 (.001) .34	−.0003 (.0003) .35	.01 (.01) .40	−.002 (.004) .54

HA = hyaluronan, AgKS = antigenic keratan sulfate, COMP = cartilage oligomeric protein, TGF-β1 = transforming growth factor- β1, JSW = joint space width. Values shown are Beta coefficients (SE) followed by p values.