. Author manuscript; available in PMC: 2009 Oct 1.

Published in final edited form as: Toxicol Appl Pharmacol. 2008 Apr 30;232(1):51–59. doi: 10.1016/j.taap.2008.04.015

Table 1.

		0.0ug/kg Mean ± SEM	2.5ug/kg Mean ± SEM	5.0ug/kg Mean ± SEM
Body Weight Grams	Male	37.71 ± 0.96	33.26 ± 1.51 ^*	35.05 ± 0.90
Body Weight Grams	Female	25.43 ± 0.49	22.83 ± 0.60 ^*	25.27 ± 1.06

Thymic Weight Grams	Male	0.061 ± 0.004	0.049 ± 0.006	0.049 ± 0.003
Thymic Weight Grams	Female	0.072 ± 0.003	0.055 ± 0.003 ^*	0.064 ± 0.004 ^*

Thymus:Body Weight Ratio	Male	0.0016 ± 0.0001	0.0015 ± 0.0002	0.0014 ± 0.0001
Thymus:Body Weight Ratio	Female	0.0028 ± 0.0001	0.0024 ± 0.0001 ^*	0.0024 ± 0.0001 ^*

Thymic Cellularity Cells (Millions)	Male	87.60 ± 9.82	79.40 ± 9.30	75.40 ± 7.19
Thymic Cellularity Cells (Millions)	Female	73.26 ± 7.37	49.02 ± 2.91 ^*	55.20 ± 6.08 ^*

Splenic Weight Grams	Male	0.09 ± 0.01	0.08 ± 0.00	0.09 ± 0.00
Splenic Weight Grams	Female	0.15 ± 0.01	0.17 ± 0.01	0.16 ± 0.01

Spleen:Body Weight Ratio	Male	0.0024 ± 0.0002	0.0025 ± 0.0001	0.0025 ± 0.0002
Spleen:Body Weight Ratio	Female	0.0058 ± 0.0004	0.0072 ± 0.0004	0.0061 ± 0.0005

Splenic Cellularity Cells (Millions)	Male	65.68 ± 13.09	61.41 ± 7.61	59.81 ± 7.48
Splenic Cellularity Cells (Millions)	Female	67.36 ± 8.42	62.87 ± 13.41	58.19 ± 7.03

n = 5 mice /treatment/gender

= p ≤ 0.05, Dunnett’s t-test.