Structural model of COMMD1. A, ab initio model with
experimental VARD in green and the empirically determined CTD in
orange. B, NMR solution structure of residues 1-108. C,
overlay of Ab initio modeled COMMD1 residues 1-108 (green)
and the NMR solution structure (cyan). D, COMMD1 model with
solution structure of residues 1-108 as initial constraint. Residues 1-108 are
shown in cyan, 109-129 in green, and the remainder of the
empirically determined CTD is orange. The proteolytic site is
indicated by the arrow.