Table 1.
Demographic Characteristics of Study Participants
| Group | N | Age (mean±SD) | Female No. (%) | Ever Smokers No. (%) | Advanced AMD No. (%) |
|---|---|---|---|---|---|
| NEI Control | 138 | 66 ± 11 | 79 (57) | 66 (48) | 0 |
| NEI AMD | 145 | 79 ± 7 | 76 (52) | 85 (59) | 109 (75) |
| AREDS Control | 193 | 77 ± 4 | 105 (54) | 94 (49) | 0 |
| AREDS AMD | 330 | 79 ± 5 | 195 (59) | 190 (58) | 297 (90) |
| BMES Control | 568 | 77 ± 8 | 344 (61) | 54 (10) | 0 |
| BMES AMD | 284 | 77 ± 8 | 172 (61) | 27 (10 ) | 54 (19) |
| MLEB Control | 22 | 64 ±12 | 12 (55) | 13 (59) | 0 |
| MLEB AMD | 46 | 75 ± 14 | 27 (57) | 19 (41) | 12 (26) |
| Total Control | 921 | 74 ± 9 | 540 (58) | 227 (25) | 0 |
| Total AMD | 805 | 78 ± 8 | 468 (58) | 321 (40)* | 472 (59) |
AMD; age-related macular degeneration; SD: standard deviation; NEI: National Eye Institute sample set; AREDS: Age-related Eye Diseases Study sample set; BMES: Blue Maintain Eye Study sample set; MLEB: Minnesota Lions Eye Bank sample set
*
Odds Ratio=2.11 (1.71, 2.61), p=4.14×10−12 in comparison with total control.