. Author manuscript; available in PMC: 2009 Nov 1.

Published in final edited form as: Ophthalmology. 2008 Aug 21;115(11):1891–1898. doi: 10.1016/j.ophtha.2008.05.021

Table 3.

Odds Ratios (95% Confidence Intervals) of the HtrA1 Promotor SNP in Age-related Macular Degeneration (AMD) Cases Stratified by Disease Stages and Subtypes after Pooling All Samples Sets

SNP	Stages		Subtypes
SNP	Early N =333	Advanced N=472	Geographic N=255	Neovascular N=249
A with respect to G	1.57 (1.14, 2.16)	2.85 (2.38, 3.40)^*	2.17 (1.75, 2.68)	2.97(2.38, 3.40)^**
	P=0.005	P=1.90×10⁻³⁰	P=8.12×10⁻¹³	P=1.66×10⁻²⁴

Non-AMD controls (n=899) as the references

Advanced stage with respect to Early stage, P=0.0001

^**

Neovascular AMD with respect to geographic AMD, p>0.05