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. Author manuscript; available in PMC: 2009 Nov 1.
Published in final edited form as: Alcohol. 2008 Nov;42(7):541–551. doi: 10.1016/j.alcohol.2008.07.001

Figure 2.

Figure 2

(A) Timeline of mean (±SEM) blood-ethanol levels in VAPOR ABST Wistar rats exposed to ethanol vapor over a period of 7 days. Dashed lines are included to denote the boundaries of the target BEL range (150–200 mg%). Tail bloods were taken from the VAPOR ABST group at 4 hr, 8 hr, 12 hr, 24 hr, 84 hr and 96 hr during the first week of exposure. The 84 hr and 96 hr time points were chosen as representative midweek time points time points at which “maximal” and “minimal” BELs, respectively, were targeted. (B) Mean (±SEM) withdrawal scores from test of physical dependence in VAPOR ABST (closed circles) and CHOICE ABST (closed triangles) rats, as well as mean (±SEM) blood-ethanol levels (open circles) for VAPOR ABST rats following removal from first week of ethanol vapor exposure. Withdrawal scores were out of 10 total possible points. Withdrawal scores were inversely related to BELs at the 6-, 8- and 10-hr time points.