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A. Dose response curve of QRFP-26 administered into the lateral ventricles of fully satiated rats fed a high fat diet. QRFP-26 (3.0nM, 5.0nM) dose-dependently increased high fat food intake at 1h, 2h and 4h following administration. B. Dose response curve of QRFP-26 administered into the lateral ventricles of rats fed a low fat diet. QRFP-26 did not alter low fat food intake. Twenty-four hour intake was not altered by any QRFP-26 dose. Data shown as mean ± SEM, *p<.05.
