TABLE 1.

Mutation rate of N. brasiliensis HUJEG-1 in response to several quinolones and SXT

Quinolone(s)a	Concn in agar
	1× the MIC	4× the MIC	16× the MIC
CIP	5.3 × 10−7	6 × 10−9	1 × 10−9
SPF	>1 × 10−9	>1 × 10−9	8 × 10−8
GAT	7.3 × 10−7	<1 × 10−9	<1 × 10−9
MXF	4.8 × 10−8	<1 × 10−9	<1 × 10−9
SXT	>1 × 10−9	6.9 × 10−8	1 × 10−9
MXF + SXT	3.4 × 10−8	<1 × 10−9	<1 × 10−9
GAT + SXT	2 × 10−9	<1 × 10−9	<1 × 10−9

^aSPF, sparfloxacin; GAT, gatifloxacin.