TABLE 1.
Susceptibilities of different BCG vaccine strains to antituberculous drugs
| Antituberculous drug | Concn (μg/ml) | Susceptibilitya of BCG strain:
|
||||
|---|---|---|---|---|---|---|
| BCG-Bulgaria (SL 222 Sofia) | BCG-Connaught | BCG-Denmark (SSI 1331) | BCG-Japan (Tokyo 172) | BCG-Medac (RIVM from 1173-P2) | ||
| First-line antituberculous drugs | ||||||
| Isoniazid | 0.1 | S | R | R | S | S |
| Isoniazid | 0.4 | S | S | S | S | S |
| Rifampin | 1.0 | S | S | S | S | S |
| Rifabutin | 0.5 | S | S | S | S | S |
| Pyrazinamide | 100.0 | R | R | R | R | R |
| Ethambutol | 5.0 | S | S | S | S | S |
| Second-line antituberculous drugs | ||||||
| Ethionamide | 5.0 | S | R | R | S | S |
| Ciprofloxacin | 1.0 | S | S | S | S | S |
| Ofloxacin | 1.0 | S | S | S | S | S |
| Streptomycin | 1.0 | S | S | S | S | S |
| Amikacin | 1.0 | S | S | S | S | S |
| Kanamycin | 5.0 | S | S | S | S | S |
| Capreomycin | 2.5 | S | S | S | S | S |
a
R, resistant; S, sensitive.