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Structure-activity relationship for N-6 3-imidazolylprolyl indenoisoquinolines
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aDifferences between the average EC50s were less than 18%. R2 values obtained for dose-response curves all exceeded 0.97, and the coefficient of variation for quadruplicate determinations at any concentration was less than 9%.
bThe OCH2O moiety bridged positions R8 and R9.
