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. 2008 Oct 27;53(1):309–311. doi: 10.1128/AAC.01216-08

TABLE 1.

MIC range, GM, and MIC50 and MIC90 values for antifungal agents against all C. neoformans (n = 86) and C. gattii (n = 42) isolates tested

Isolate and antifungal agent MIC range GM MIC50 MIC90
Cryptococcus neoformans
    Amphotericin B 0.03-1 0.186 0.25 0.5
    Flucytosine 0.25-16 3.6 4 8
    Fluconazole 0.25-64 1.95 2 4
    Posaconazole <0.015-0.5 0.034 0.03 0.06
    Voriconazole <0.015-0.5 0.069 0.06 0.25
    Isavuconazole <0.015-0.5 0.023 <0.015 0.06
Cryptococcus gattii
    Amphotericin B 0.125-1 0.24 0.25 0.25
    Flucytosine 0.06-16 1.97 2 8
    Fluconazole 0.5-32 2.36 2 8
    Posaconazole <0.015-0.25 0.041 0.03 0.125
    Voriconazole <0.015-0.5 0.098 0.125 0.25
    Isavuconazole <0.015-0.25 0.026 0.03 0.06