FIG. 2.

Live C. albicans suppresses ROS production in a dose-dependent manner. ROS production by J774 cells was measured in response to live or HK yeast at the indicated yeast/phagocyte ratio. Each experiment was performed with triplicate samples; the bar heights indicates the mean values and error bars represent the standard deviations. A representative experiment is presented; the experiment was repeated three times with the same trend observed each time. Live yeast resulted in significantly less ROS production than HK yeast at each yeast/phagocyte ratio (two-way ANOVA, P < 0.001 overall; for all individual yeast/phagocyte ratios, post hoc Student's t test comparisons yielded P values <0.001).