FIG. 4.

Candida species suppress ROS production but S. cerevisiae does not. ROS production by J774 cells in response to HK or live yeast was measured as for Fig. 1. A representative experiment is presented; the experiment was repeated three times, with the same trend observed each time. Each experiment was performed with triplicate samples; the bar heights indicates the mean values and error bars represent the standard deviations. Results were analyzed using a two-way ANOVA; ROS production in response to live S. cerevisiae was significantly different than with either of the Candida species (P < 0.001 for all comparisons). Live yeast induced less ROS than HK for both Candida species (P < 0.001 for both comparisons).