FIG. 1.

ALL1 expression in SM and MC variants and high levels of homology of the ALL1 protein in C. neoformans serotypes. (a) Comparison of ALL1 in SM and MC variants during intracellular growth in macrophages by using RT-PCR. In two different macrophage experiments (black bar and gray bar) ALL1 was more highly expressed at 2 and 8 h. Expression was measured relative to actin expression, and similar results were obtained with glyceraldehyde-3-phosphate dehydrogenase. Standard deviations were determined by using triplicate measurements for RT-PCR and are indicated by the error bars. (b) High levels of homology of the putative protein sequences in C. neoformans serotype D, A, and B strains.