FIG. 5.

A marked decrease in colon IL-17 following infection of NK1.1-depleted mice correlates with enhanced bacterial dissemination from the gut. Two groups of B6 mice were depleted of NK1.1 cells and then infected orally with Salmonella or left uninfected. Two groups of control mice were not depleted of NK1.1 cells but otherwise were treated identically. At 48 h following infection, IL-17 levels (A and C) or IFN-γ levels (B and D) were measured in the small intestine and colon using an ELISA. Data are the means with standard errors. White circles in panel C denote two animals with undetectable levels of IL-17.