TABLE 3.
Detection of HEV RNAa
| Group | Pig no. | Result (fecal/serum) at week p.i.:
|
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | ||
| A (sHVRd1) | 286 | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− |
| 296 | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− | |
| 608 | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− | |
| B (sHVRd2) | 291 | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− | +/− | −/− |
| 295 | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− | +/− | +/− | |
| 613 | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− | |
| C (sHVRd3) | 292 | −/− | −/− | +/− | +/− | +/− | +/− | +/− | +/− | +/− | +/− | ++/−/− |
| 604 | −/− | −/− | −/− | +/+ | −/− | +/− | +/+ | +/− | +/− | −/− | +/− | |
| 606 | −/− | −/− | +/− | +/− | +/− | +/− | +/− | +/− | +/− | +/− | +/− | |
| D (sHVRd4) | 288 | −/− | −/− | +/− | +/− | +/− | +/+ | +/− | +/− | +/− | +/− | −/− |
| 293 | −/− | −/− | +/− | +/− | +/− | −/− | −/− | −/− | +/− | −/− | +/− | |
| 300 | −/− | −/− | −/− | +/− | +/− | +/− | +/− | −/− | +/− | −/− | +/− | |
| E (wild-type clone) | 289 | −/− | −/− | −/− | −/− | −/− | +/− | +/− | −/− | −/− | −/− | −/− |
| (Positive control | 294 | −/− | −/− | +/− | +/+ | +/− | +/− | −/− | −/− | −/− | −/− | −/− |
| group) | 612 | −/− | −/− | −/− | −/− | +/− | +/− | −/− | +/− | −/− | +/− | −/− |
| F (negative control | 603 | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− |
| group) | 609 | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− |
| 611 | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− | −/− | |
a
In samples that were positive (+) or negative (−) at the indicated week p.i. in SPF chickens intrahepatically inoculated with capped RNA transcripts of swine HEV HVR deletion mutants, as well as the wild-type infectious clone.