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. 2008 Oct 22;83(1):159–166. doi: 10.1128/JVI.01211-08

FIG. 2.

FIG. 2.

LCMV-induced CD8+ T-cell responses after i.o. infection. C57BL/6 mice were infected i.o. with 103 PFU of LCMV Arm, WE, and Docile (Doc), and CD8+ T-cell responses were analyzed on day 12 postinfection. (A) Representative dot blots from MHC-I tetramer analysis for the indicated viral strain. Values in the upper right quadrants indicate percentages of H-2Db/gp33-binding cells within the CD8+ T-cell compartment. (B) Mean percentages ± SEM of gp33 tetramer (tet)-positive cells in the CD8+ T-cell compartment (Arm, n = 3 mice; WE, n = 3 mice; Docile, n = 3 mice). (C) CTL reactivity determined by intracellular IFN-γ secretion in response to restimulation with LCMV gp33 and np396 peptides. Values are mean percentages ± SEM of IFN-γ-secreting cells within the CD8+ T-cell compartment (Arm, n = 3 mice; WE, n = 3 mice; Docile, n = 3 mice).