TABLE 2.
Nuclear and cytoplasmic distribution of capsids in WT and mutant HSV-1-infected cells
| Virus and capsid type | Nuclear
|
Cytoplasmic
|
|||
|---|---|---|---|---|---|
| No. of capids | % of total nuclear capsids | No. of free capids | No. of aggregated capsids | % of total DNA-containing capsids | |
| WT HSV-1 | |||||
| A | 154 | 17 | 2 | ||
| B | 691 | 76 | 2 | ||
| C | 63 | 7 | 40 | ||
| Virionsa | 217 | ||||
| FRΔUL37 | |||||
| A | 227 | 13 | 2 | 3 | |
| B | 1,380 | 77 | 4 | 21 | |
| C | 177 | 10 | 39 | 425 | 72 |
| KΔUL36 | |||||
| A | 107 | 14 | 17 | 1 | |
| B | 586 | 77 | 10 | 2 | |
| C | 71 | 9 | 149 | 324 | 87 |
| ARΔUL36 | |||||
| A | 161 | 19 | 13 | ||
| B | 544 | 66 | 68 | ||
| C | 123 | 15 | 276 | 69 | |
Includes enveloped cytoplasmic and extracellular capsids.