FIG. 2.
Comparison of the nucleotide sequences and secondary structures of the SLA structures of different DENV serotypes. (A) Alignment of the consensus sequences of the first 70 nucleotides of DENV1, DENV2, DENV3, and DENV4. The regions corresponding to the predicted secondary structures S1, S2, S3, TL, and SSL of DENV2 are indicated on the top. Nucleotide variation between DENV2 and the other three serotypes is indicated in bold. Underlined nucleotides indicate covariations. (B) Comparative RNA secondary structure analysis predicted for the SLA structures of the four DENV serotypes. The nucleotide differences between DENV2 and the other three serotypes are indicated in bold.