FIG. 5.

Genital inflammation and disease after i.vag. challenge of immunized mice. Mice immunized and challenged as described in the legend to Fig. 4 were observed daily for signs of inflammation and lesions on their external genitalia. Mice were immunized with high (A), medium (B), or low (C) doses of 5BlacZ or 5B86 or an amount of control supernatant corresponding to the high dose of virus. Data represent the arithmetic mean ± SEM for all samples compiled from four independent experiments (n = 15 for control; n = 20 for 5BlacZ and 5B86). *, P value of ≤0.027 for 5B86 compared with 5BlacZ.