TABLE 1.
Plasma cytokine and chemokine levels at week 2 after SIV infection
| Animal species (virus) | n | Mean pg/ml ± SEM
|
|||||||
|---|---|---|---|---|---|---|---|---|---|
| IL-2 | IL-6 | IFN-γ | RANTES | MIG | MCP-1 | IP-10 | IL-8 | ||
| SM (SIVsmE041) | 4 | 15.2 ± 0.9 | 1.9 ± 0.7 | 3.5 ± 0.79 | 6,100 ± 1469 | 11 ± 3.5 | 411.6 ± 102 | 62.3 ± 25.3 | 802 ± 94.7 |
| RM (SIVmac239) | 6 | 14.4 ± 5.4 | 5.7 ± 3.4 | 2.5 ± 1.2 | 17,763 ± 2999 | 15.2 ± 5.6 | 327 ± 38 | 31.6 ± 12.9 | 1,241 ± 229 |
| P valuea | 0.9 | 0.41 | 0.58 | 0.01 | 0.59 | 0.39 | 0.26 | 0.17 | |
a
Determined by the two-tailed unpaired t test. Detection limits of the cytometric bead array were as follows: IL-2, 0.6 pg/ml; IL-6, 0.1 pg/ml; IFN-γ, 3.3 pg/ml; IL-8, 0.2 pg/ml; RANTES, 1.0 pg/ml; MIG, 2.5 pg/ml; MCP-1, 2.7 pg/ml; IP-10, 2.8 pg/ml.