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Susceptibility of S. mutans to lysozyme. S. mutans wild type and the pgdA knockout were grown in TH broth. In the early exponential phase or at the beginning of the stationary phase (as indicated by the arrows), lysozyme (40 μg/ml) was added to the experimental cultures. (A and C) Wild-type strain; (B and D) pgdA knockout. Solid symbols indicate the control cultures without the addition of lysozyme. Open symbols indicate the cultures treated with lysozyme.
