Fig. 1.

Study design and timeline in hours. Schematic displaying the study design used to measure the effect of resistance exercise on the regulation of whole body fat and glucose oxidation, glucose uptake, and cell signaling in male subjects. The study design consisted of a baseline, exercise, 1-h postexercise, and 2-h postexercise period. Continuous breath sampling was obtained with a Sensor Medics Vmax series metabolic cart. Indocyanine green (ICG) was infused to measure blood flow during each period. Blood samples were collected to measure plasma glucose and insulin and blood flow and to calculate glucose uptake. Muscle biopsies were used to measure muscle cell signaling, specifically components upstream and partially responsible for the activation of Akt substrate of 160 kDa (AS160).