Table 2.
Animal characteristics
| NC-Sed | NC-Ex | HC-Sed | HC-Ex | |
|---|---|---|---|---|
| Body weight, kg | 42.9±1.1 (40) | 39.9±1.1 (20) | 45.5±1.1† (37) | 41.8±1.2 (16) |
| Heart wt/body wt, g/kg | 4.3±0.1 | 5.6±0.1‡ | 3.9±0.1 | 5.6±0.2‡ |
| Total cholesterol, mg/dl | ||||
| Baseline | 64±2 (40) | 56±4 (20) | 61±3 (36) | 58±3 (15) |
| 4 wk | 58±2 | 51±4 | 366±21* | 353±45* |
| Termination | 58±2 | 58±2 | 416±25* | 433±40* |
| LDL cholesterol, mg/dl | ||||
| Baseline | 23±2 (24) | 21±5 (5) | 23±2 (22) | 24±1 (8) |
| 4 wk | 19±2 | 15±3 | 167±17* | 196±33* |
| Termination | 19±2 | 22±2 | 190±18* | 218±22* |
| Citrate synthase, μmol·min−1·g−1 Deltoid | 15.8±1.2 (22) | 20.7±1.1‡ (20) | 14.7±0.8 (21) | 22.4±1.3‡ (16) |
| Triceps brachii | ||||
| Long head | 12.4±0.9 | 18.9±1.9‡ | 11.5±0.8 | 16.1±1.3‡ |
| Lateral head | 9.7±0.8 | 14.9±1.1‡ | 11.1±0.9 | 17.4±1.1‡ |
| Medial head | 13.5±0.9 | 18.8±1.5‡ | 15.2±1.0 | 22.4±0.8‡ |
Values are mean ± SE. Numbers in parentheses are the number of animals studied for each data subset. NC, normal cholesterol; HC, hypercholesterolemic; Sed, sedentary; Ex, exercise trained.
*
P ≤ 0.05 HC vs. NC;
†
P ≤ 0.05 HC-Sed vs. NC-Ex;
‡
P ≤ 0.05 Ex vs. Sed.