Table 3.
Dimensional characteristics of coronary arterioles
NC-Sed (n = 67) | NC-Ex (n = 15) | HC-Sed (n = 33) | HC-Ex (n = 14) | |
---|---|---|---|---|
Passive diameter, μm | 146±5 | 173±10 | 147±6 | 164±11 |
%Preconstriction | 58±2 | 45±8* | 64±2 | 49±6 |
ET-1, [nM] | 0.5±0.1 | 0.5±0.1 | 0.5±0.1 | 0.5±0.1 |
Values are mean ± SE; n indicates number of arterioles studied. NC, normal cholesterol; HC, hypercholesterolemic; Sed, sedentary; Ex, exercise trained; %preconstriction, %maximal diameter to which arterioles were preconstricted; ET-1, concentration of endothelin-1 required to obtain %preconstriction.
Significantly lower level of preconstriction than NC-Sed and HC-Sed.