TABLE 2.
Genotypic analysis of embryos derived from Rb+/−; E2f3b−/− intercrossesa
| Genotype | No. of embryos at day:
|
|||||||
|---|---|---|---|---|---|---|---|---|
| E13.5
|
E15.5
|
E16.5
|
E17.5
|
|||||
| Found | Expected | Found | Expected | Found | Expected | Found | Expected | |
| Rb+/+3b−− | 13 | 14 | − | − | 17 | 14 | − | − |
| Rb+/−3b−− | 30 (2) | 28 | − | − | 24 | 28 | − | − |
| Rb−/−3b−− | 9 (5)A | 14 | − | − | 0B | 14 | − | − |
| Total | 59 | 41 | ||||||
a
All embryos, including dead embryos, were genotyped. The numbers of genotyped dead fetuses are indicated in parentheses. −, no embryos with this genotype were found. Chi-square analysis was used for association (superscript capital letters): A, P > 0.1 compared to Rb+/+ mice; B, P < 0.001 compared to Rb+/+ mice.