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. 2008 Dec;125(4):459–468. doi: 10.1111/j.1365-2567.2008.02866.x

Figure 5.

Figure 5

OX40 is involved in development of GVHD. (a, b) disease incidence and severity in adoptive hosts of naïve T cells FACS purified from OX40-deficient mice (n = 5, dotted lines), OX40 Cre B6 R26R EYFP reporter mice (n = 4, dashed lines), compared with wild type naïve T cells (n = 8, solid lines). (c) Percentage of YFP-positive CD4 T cells in recipients of sorted YFP negative naïve T cells from OX40 Cre B6 R26R EYFP reporter mice assessed 2 weeks after transfer. The data is representative of two independent experiments with between two and five recipients per group. (d) Cell recovery from recipients of wildtype (white bar) or OX40−/− naïve T cells (black bar) 8 weeks after transfer. The data shown is representative of two independent experiments with three to four mice per group.